ON SUCCESSIVE DUPLICATE MUTATIONS
نویسندگان
چکیده
منابع مشابه
Role of Duplicate Genes in Robustness against Deleterious Human Mutations
It is now widely recognized that robustness is an inherent property of biological systems [1],[2],[3]. The contribution of close sequence homologs to genetic robustness against null mutations has been previously demonstrated in simple organisms [4],[5]. In this paper we investigate in detail the contribution of gene duplicates to back-up against deleterious human mutations. Our analysis demonst...
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The origin of organismal complexity is generally thought to be tightly coupled to the evolution of new gene functions arising subsequent to gene duplication. Under the classical model for the evolution of duplicate genes, one member of the duplicated pair usually degenerates within a few million years by accumulating deleterious mutations, while the other duplicate retains the original function...
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ژورنال
عنوان ژورنال: The Biological Bulletin
سال: 1915
ISSN: 0006-3185,1939-8697
DOI: 10.2307/1536409